Homology Effects

Homology Effects offers contributions from an international panel of researchers whose aim has been both to introduce newcomers to the field of homology effects, and to bring colleagues up to date. Topic coverage includes dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, RNAi and antisense biology, homology effects in ciliates, prion biology, and a discourse on the evolution of gene duplications. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.

Klappentext
Homology Effects offers contributions from an international panel of researchers whose aim has been both to introduce newcomers to the field of homology effects, and to bring colleagues up to date. Topic coverage includes dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, RNAi and antisense biology, homology effects in ciliates, prion biology, and a discourse on the evolution of gene duplications. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.

Zusammenfassung
Intends to introduce newcomers to the field of homology effects. This title covers such topics as dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, and RNAi and antisense biology.

Inhalt
1. Sex and the Single Chromosome 2. Is X-Chromosome Inactivation a Homology Effect? 3. Homologous Chromosome Associations and Nuclear Order in Meiotic and Mitotically Dividing Cells of Budding Yeast 4. The Role of Sequence Homology in the Repair of DNA Double-Strand Breaks in Drosophila 5. The Origins of Genomic Imprinting in Mammals 6. Genomic Imprinting During Seed Development 7. Long-Distance Cis and Trans Interactions Mediate Paramutation 8. Homology-Dependent Gene Silencing and Host Defense in Plants 9. Quelling in Neurospora crassa 10. Non-Mendelian Inheritance and Homology-Dependent Effects in Ciliates 11. RNAi (Nematodes: Caenorhabditis elegans) 12. Antisense RNAs in Bacteria and Their Genetic Elements 13. Transvection in Drosophila 14. Pairing-Sensitive Silencing, Polycomb Group Response Elements, and Transposon Homing in Drosophila 15. Repeat-Induced Gene Silencing in Fungi 16. The Evolution of Gene Duplicates 17. Prions of Yeast as Epigenetic Phenomena: High Protein "Copy Number? Inducing Protein "Silencing?

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