Understanding Medical Research

Medical students and junior and senior doctors are frequently
called upon to give research presentations, write reports, and
answer exam questions on specific areas of medical research.

Understanding Medical Research: The Studies That Shaped
Medicine is an exciting new title that offers a unique and
valuable approach to understanding historically influential studies
in important areas of medicine.

Featuring chapters from Sir Liam Donaldson and Sir David
Weatherall, amongst others, world leading researchers identify ten
primary research papers that have shaped the direction of research
in their given topic, examining why they were carried out, key
findings, and how they changed the field.

Each chapter also contains short sections on 'Key
Questions Remaining' which outline outstanding areas where
further research is needed, and a link to 'Key
Laboratories/Clinics' which point the reader to major
research groups of international standing.

Covering the seminal research in core areas of medicine,
Understanding Medical Research provides an authoritative
framework on each topic for medical students and healthcare
professionals.

Autorentext
John A. Goodfellow, BM BCh, PhD, is Honorary Clinical Academic Fellow at the University of Glasgow

Zusammenfassung
Medical students and junior and senior doctors are frequently called upon to give research presentations, write reports, and answer exam questions on specific areas of medical research. Understanding Medical Research: The Studies That Shaped Medicine is an exciting new title that offers a unique and valuable approach to understanding historically influential studies in important areas of medicine. Featuring chapters from Sir Liam Donaldson and Sir David Weatherall, amongst others, world leading researchers identify ten primary research papers that have shaped the direction of research in their given topic, examining why they were carried out, key findings, and how they changed the field. Each chapter also contains short sections on 'Key Questions Remaining' which outline outstanding areas where further research is needed, and a link to 'Key Laboratories/Clinics' which point the reader to major research groups of international standing. Covering the seminal research in core areas of medicine, Understanding Medical Research provides an authoritative framework on each topic for medical students and healthcare professionals.

Inhalt
Contributors, ix Preface, xiv Foreword, xv
Sir Liam Donaldson Acknowledgements, xvi Chapter 1 Population Health, 1
Douglas Noble, Felix Greaves and Sir Liam Donaldson Chapter 2 Patient Safety, 14
Felix Greaves, Douglas Noble and Sir Liam Donaldson Chapter 3 Heart Failure, 24
Martin R. Cowie and Kaushik Guha Chapter 4 Acute Coronary Syndrome (NSTEMI), 34
Wei Yao Lim and Colin Berry Chapter 5 Lipids, Dyslipidaemia and Cardiovascular Disease, 46
Gilbert R. Thompson Chapter 6 Atrial Fibrillation, 58
Kunihiro Nishida and Stanley Nattel Chapter 7 Asthma, 69
Tak H. Lee and Leonard Siew Chapter 8 Cystic Fibrosis, 81
Andrew Bush Chapter 9 Chronic Obstructive Pulmonary Disease, 92
Paul A. Ford and Peter J. Barnes Chapter 10 Pneumonia, 103
John M. Wrightson, Eleanor K. Mishra and Robert J.O. Davies Chapter 11 Stroke, 115
Philip M.W. Bath and Nikola Sprigg Chapter 12 Parkinson's Disease, 127
Edward J. Newman and Donald G. Grosset Chapter 13 Epilepsy, 138
Fergus J. Rugg-Gunn Chapter 14 Motor Neuron Disease, 151
Martin R. Turner and Kevin Talbot Chapter 15 Migraine, 162
Mark W. Weatherall Chapter 16 Multiple Sclerosis, 171
Alasdair Coles and Alastair Compston Chapter 17 The Autoimmune Basis for Guillain-Barr_e Syndrome, 183
John A. Goodfellow and Hugh J. Willison Chapter 18 Helicobacter pylori, Peptic Ulcers and Gastric Cancer, 193
Anahita Dua and Emad M. El-Omar Chapter 19 Acute Liver Failure, 204
James O'Beirne and Andrew K. Burroughs Chapter 20 Haemostasis and Thrombosis, 216
Charles Percy and Raza Alikhan Chapter 21 The Inherited Disorders of Haemoglobin, 224
Sir David Weatherall Chapter 22 Diabetes Therapy and the Prevention of Vascular Damage, 235
Philip Home Chapter 23 Rheumatoid Arthritis, 246
Jonathan C.W. Edwards and Maria J. Leandro Chapter 24 Osteoarthritis, 254
Kirsten White, Alexander S. Nicholls, Anushka Soni and Nigel Arden Chapter 25 Systemic Vasculitis, 263
Joanna Robson, Ravi Suppiah and Raashid Luqmani Chapter 26 Polycystic Kidney Disease, 275
Qi Qian Chapter 27 Glomerular Disease and the Nephrotic Syndrome, 285
Jenny Papakrivopoulou and Robert Unwin Chapter 28 Acquired Immunodeficiency Syndrome, 296
Tica Pichulik and Alison Simmons Chapter 29 Transplantation, 309
Elizabeth Simpson Chapter 30 Autoimmunity, 320
Jonathan C.W. Edwards and Geraldine Cambridge Chapter 31 The Biochemistry of Depression, 329
Philip J. Cowen Chapter 32 Schizophrenia and the Dopamine Hypothesis, 338
Mandy Johnstone and Eve C. Johnstone Chapter 33 Alzheimer's Disease, 349
Gordon Wilcock and Alistair Burns Index, 361

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