Proteomics of the Nervous System

Combing the cutting-edge technology of proteomics with the hugely-important field of neuroscience - covering applications in both biomedical and basic research. Gives theoretical bases, protocols, and cases studies of application of proteomics to brain and neural research.

Der derzeit einzige lieferbare Titel zum Thema Proteomik, der diese mit den Neurowissenschaften verknüpft. Er gibt einen Überblick über aktuellen Forschungsstand und theoretische Grundlagen und präsentiert Anwendungsprotokolle relevanter proteomischer Schlüsseltechnologien.

Autorentext
Professor Pfeiffer has been professor in the University of Connecticut since 1969, and has carried out research in many different countries including France, Germany and Japan. He has served as the president of the International Society for Developmental Neurobiology, and as a member of the council of the International Society for Neurochemistry. He is a member of numerous scientific societies, and is on the editorial boards of many journals including the Journal of Neuroscience Research. He is author of over 100 scientific publications.

Dr Nothwang carried out his PhD in the Jacque Monod Institute in Paris, France, before carrying out postdoctoral work in Tokushima, Japan, and Freiburg, Germany. Since 2001 he has been working as a research associate in the University of Kaiserslautern, Germany, where his work focuses on proteomic analyses of the nervous system.

Inhalt
From the contents:
THEORETICAL FOUNDATIONS
Biological reality in the brain
Protein complexes
The human brain proteome project
APPLICATION TO BASIC NEUROSCIENCE
Comparative protein analysis between mouse strains
Proteomics in evolutionary studies
Proteome analysis of plasma membranes
Proteome analysis of synaptic vesicles
Protein analysis of a potassium channel
Analysis of posttranslational modifications
Paranodal structure and function - ion channel localization
BIOMEDICAL RESEARCH
Probing the huntingtin interaction network
Proteomic analysis of the myelin membrane - application to demyelinating disease
New insights into Alzheimer's disease
Nerve injury
Diseases biomarkers

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