Autor:
Peter H. Wiernik, John M. Goldman, Janice P. Dutcher, Robert A. Kyle
Erscheinungsdatum:
22.09.2012
Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia- Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth section covers a variety of topics in supportive care. Now in its fifth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. Chapters feature an accessible and easy-to-read layout and provide updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. An authoritative and indispensable resource for students, trainees, and clinicians, this fifth edition is sure to distinguish itself as the definitive reference on this topic.
Klappentext
Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth section covers a variety of topics in supportive care. Now in its fifth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. Chapters feature an accessible and easy-to-read layout and provide updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. An authoritative and indispensable resource for students, trainees, and clinicians, this fifth edition is sure to distinguish itself as the definitive reference on this topic.
Inhalt
Part I: Chronic Leukemias and Related Disorders
1: A History of the Chronic Leukemias
John M. Goldman and Myrtle Y. Gordon
2: Etiology and Epidemiology of Chronic Myeloid Leukemia
Maren Rohrbacher and Joerg Hasford
3: Pathology of the Chronic Myeloid Leukemias
Barbara J. Bain
4: Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia
Alfonso Quintás Cardama, Hagop Kantarjian, and Jorge Cortes
5: Diagnosis and Treatment of Chronic Myeloid Leukemia
Stephen G. O'Brien and John M. Goldman
6: Etiology and Epidemiology of CLL
Dalemari Crowther-Swanepoel, Daniel Catovsky, and
Richard S. Houlston
7: Histopathology, Morphology, and Immunophenotyping of CLL
Abraham M. Varghese, Andy C. Rawstron, Roger G. Owen, and Peter Hillmen
8: Molecular Biology and Cytogenetics of Chronic Lymphocytic Leukemia
David Oscier, Anne Gardiner, and Jonathan C. Strefford
9: Treatment of Chronic Lymphocytic Leukemia and Related Disorders
Gautam Borthakur and Susan O'Brien
10: Hairy Cell Leukemia
Sejal A. Jhatakia, Darren S. Sigal, and Alan Saven
11: The Pathogenesis, Diagnosis, and Treatment of Polycythemia Vera
Mark A. Dawson and Brian J.P. Huntly
12: Diagnosis and Treatment of Essential Thrombocythemia and Primary Myelofibrosis
John T. Reilly
Part II: Acute Leukemias
13: History of Acute Leukemia
Emil J Freireich
14: The Etiology of Acute LeukemiaJessica N. Nichol, Sarit Assouline, and Wilson H. Miller
15: Epidemiology and Hereditary Aspects of Acute Leukemia
Martha S. Linet, Graca M. Dores, Clara J. Kim, Susan S. Devesa, and Lindsay M. Morton
16: Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations
Nukhet N. Tuzuner and John M. Bennett
17: Immunobiology of Acute LeukemiaElisabeth Paietta
18: Cytogenetics of Acute Leukemia
Nyla A. Heerema and Susana Catalina Raimondi
19: Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia
Dario Campana and Ching-Hon Pui
20: Diagnosis and Treatment of Adult Acute Lymphoblastic Leukemia
Nicola Goekbuget and Dieter Hoelzer
21: Diagnosis and Treatment of Childhood Acute Myeloid Leukemia
David A. Sweetser and Howard J. Weinstein
22: Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other Than Acute Promyelocytic Leukemia
Peter H. Wiernik
23: Acute Promyelocytic Leukemia
Peter H. Wiernik, Robert E. Gallagher, and Martin S. Tallman
24: Therapy-Related Acute Myelogenous Leukemia
Gabriela Bernadeta Iwanski, Nils Heinrich Thoennissen, Dorothy J. Park, and H. Phillip Koeffler
25: The Myelodysplastic Syndromes
Kenneth Miller and Igor Rozenvald
Part III: Myeloma and Related Diseases
26: History of Multiple Myeloma
David P. Steensma and Robert A. Kyle
27: Cytokines and Signal Transduction in Multiple Myeloma
Dharminder Chauhan and Kenneth C. Anderson
28: Epidemiology of Multiple Myeloma
Dalsu Baris, Linda Morris Brown, Gabriella Andreotti, and Susan S. Devesa
29: Immunoglobulins and Laboratory Recognition of Monoclonal Proteins
Jerry Katzmann, Robert A. Kyle, John Lust, Melissa Snyder, and Angela Dispenzieri
30: Cytogenetic Abnormalities in MGUS and Myeloma
Rafael Fonseca, P. Leif Bergsagel, and W. Michael Kuehl
31: Molecular Genetics of Myeloma
Brian Van Ness
32: Prognosis and Staging of Multiple Myeloma
Jesús F. San-Miguel, Ramón García-Sanz, and Norma C. Gutiérrez
33: Diagnosis and Treatment of Multiple Myeloma
S.Vincent Rajkumar and Robert A. Kyle
34: Complications and Special Presentations of Plasma Cell Myeloma
Joan Bladé and Laura Rosiñol
35: Waldenström's Macroglobulinemia
Efstathios Kastritis and Meletios A. Dimopoulos
36: Heavy-Chain Disease
Dietlind L. Wahner-Roedler and Robert A. Kyle
37: Diagnosis and Therapy of Immunoglobulin Light Chain Amyloidosis (AL Amyloidosis)
Morie A. Gertz and Robert A. Kyle
38: Monoclonal Gammopathy of Undetermined Significance
Robert A. Kyle and S. Vincent Rajkumar
Part IV: Lymphoma
39: Historical Landm...
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